Pseudogout: When Calcium Crystals Affect the Joints
Blog

Pseudogout: When Calcium Crystals Affect the Joints

Introduction

A sudden flare-up of the joint pain can leave anyone wondering what’s actually going on and doubting the seriousness of the condition. Due to the similarity in symptoms between gout and pseudogout, which is also called calcium pyrophosphate dihydrate crystal deposition disease (CPPD), a microscopic analysis is usually needed to verify the diagnosis. However, it is possible that both gout and pseudogout occur at the same time.

Treatments for these types of inflammatory arthritis vary depending on the specific type of crystals that are deposited in the joints and causing symptoms. Unlike other arthritic diseases, pseudogout can be managed well with accurate treatment. With timely diagnosis and the right treatment, gout can be treated fully. 

Both these diseases happen due to the deposition of crystals, but the crystals vary in composition and structure. Therefore, these conditions call for different treatment approaches. In the following article, we will delve deeper into pseudogout symptoms, exploring how it can affect us and discussing effective management strategies.

What is Pseudogout?

Pseudogout is a type of inflammatory arthritis characterized by abrupt and severe swelling in one or more joints. Episodes of flare-ups can span several days or weeks.

Pseudogout is actually known as calcium pyrophosphate deposition disease (CPPD). Since the condition resembles gout, it is usually referred to as pseudogout. Crystal deposits grow within joints in both pseudogout and gout, but the type of crystal differentiates the two conditions.

It's not clearly understood why crystals grow in joints, causing pseudogout. However, it is seen that the risk rises with age. Treatments can help in alleviating the pain and inflammation.

Which Joints Are Affected By Pseudogout?

This condition can affect any joint of the body, but it usually occurs in:

What are the Causes of Pseudogout?

Pseudogout is caused by a buildup of calcium pyrophosphate (CPP) in the impacted joints. The excess CPP clumps together and results in deposition of tiny crystals that accumulate inside the joint structures. This results in the flaring up of pseudogout symptoms such as pain and immobility.

The exact causes of pseudogout are under research. Some studies suggest that it may be inherited, which means that parents can pass on the risk of getting pseudogout to their children. Some people may experience it due to trauma or joint injury. Certain metabolic or endocrine disorders also increase the risk of this condition. The following health conditions raise the risk of pseudogout:

  • Hypomagnesemia (low magnesium levels)
  • Thyroid disease
  • Hyperparathyroidism (excess parathyroid hormone)
  • Hemochromatosis (iron overload)
  • Hypophosphatasia (disorder of bone and mineral metabolism)
  • Osteopenia (reduced bone density)
  • Chronic kidney disease (CKD)
  • Gout
  • Osteoarthritis (degenerative joint disease)
  • Rheumatoid arthritis (autoimmune chronic inflammatory arthritis)
  • Post-traumatic arthritis

What are the Signs of Pseudogout?

The signs of pseudogout appear and disappear. The appearance of symptoms is called "flare-ups" or "attacks." The following are the symptoms associated with pseudogout:

  • Sudden and intense joint pain
  • Skin discoloration 
  • Redness of the skin
  • Swelling
  • Joint stiffness
  • Heat or warmth in or around a joint

Pseudogout Vs. Gout

Pseudogout differs from gout in the following aspects:

Aspect Gout Pseudogout (CPP arthritis)
Meaning of name Named after uric acid–related arthritis Called “false gout” due to similar symptoms
Cause Excess uric acid in the blood (hyperuricemia) Buildup of calcium pyrophosphate crystals
Type of crystals Uric acid crystals Calcium pyrophosphate (CPP) crystals
Alternative name Calcium pyrophosphate deposition disease (CPPD)
How crystals form Uric acid crystals clump together in joints Calcium pyrophosphate is deposited in joints
Most commonly affected joint Big toe joint (metatarsophalangeal or MTP joint) Larger joints such as the knee, wrist, or shoulder
Joint involvement pattern Often starts in the big toe Rarely affects the big toe

How is the Diagnosis of  Pseudogout Made?

The following tests help in diagnosing pseudogout:

  1. Personal family history
  2. Symptom analysis
  3. Physical examination
  4. Joint aspiration (arthrocentesis)
  5. X-rays
  6. CT scan (computed tomography scan)
  7. MRI (magnetic resonance imaging)
  8. Ultrasound

What is the Treatment for Calcium Crystal Arthritis?

The most common treatments for pseudogout include medications for reducing the inflammation and stopping the crystal formation. These medications are:

  • NSAIDs to relieve pain and reduce inflammation
  • Corticosteroids in the pill form or injectable shots
  • Colchicine to reduce inflammation and pain, especially during flares
  • Biologic injections to manage pseudogout attacks

Prevention Tips for Pseudogout

There is currently no technique for preventing pseudogout. However, experts are still trying to pin down exactly what triggers your body to create the excess CPP that causes it. Flares of symptoms can be less frequent if you take care of any underlying health issues you may have.

In fact, some individuals are more prone to experiencing symptoms than others. Experiencing a pseudogout attack is completely out of your control and has nothing to do with your actions. In most cases, there are no obvious causes (triggers) that you can control.

Conclusion

Pseudogout may refer to "false" gout, but the pain, swelling, and discomfort you're experiencing are real. It's upsetting to realize that you cannot prevent pseudogout. However, most people may find relief with a combination of drugs that reduces the intensity and frequency of pain that interferes with their everyday activities. You'll probably still have flares from time to time, but your doctor will help you find strategies to manage your symptoms.

Get expert pseudogout treatment in Dwarka from Dr. Ishwar Bohra. Book your consultation now!

FAQs

Q1: Can pseudogout be permanently cured?

A: There is no permanent cure for pseudogout, but timely treatment can effectively control symptoms, reduce flare frequency, and improve joint function.

Q2: If I have both gout and pseudogout, can a single treatment help?

A: In some cases, a combined treatment approach may help manage both conditions, but medications are selected based on the type of crystals involved and must be tailored by a specialist.

Q3: Where can I get the best pseudogout treatment in Dwarka?

A: You can consult Dr. Ishwar Bohra in Dwarka for expert evaluation and personalized treatment of pseudogout and other crystal-induced arthritis conditions.

Q4: How is pseudogout different from osteoarthritis?

A: Pseudogout is caused by calcium crystal deposition and presents with sudden inflammatory flare-ups, while osteoarthritis is a degenerative joint condition that progresses gradually over time.

Q5: Is pseudogout a chronic condition?

A: Yes, pseudogout can be chronic in some people, with recurrent flare-ups over time, but symptoms can be well controlled with proper treatment.
 

Related Blogs

CONTACT US

We Are
Available 24X7

Get in touch with us and get your queries solved. Avail the best advice and guidance for your treatment. Call us or write to us to avail prompt assistance. Our team will connect with you as soon as possible.

  • Phone+91-9582280201

  • Emailishwar.bohra@gmail.com
    anandrishma@gmail.com

Choose Files Drag & drop here or select files

Latest Updates

Get the Latest News & Updates

Staying abreast with the latest information is the best way to combat diseases in early stages and live a healthy life. Read the latest news & updates here to learn about the recent advancements in joint care and therapeutics.

View All Articles